Ontology highlight
ABSTRACT:
SUBMITTER: Wang GW
PROVIDER: S-EPMC5073370 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Wang Gang-Wei GW Wang Gang-Wei GW McCreanor Niall G NG Shaw Megan H MH Whittingham William G WG Bower John F JF
Journal of the American Chemical Society 20161006 41
Under carbonylative conditions, neutral Rh(I)-systems modified with weak donor ligands (AsPh<sub>3</sub> or 1,4-oxathiane) undergo N-Cbz, N-benzoyl, or N-Ts directed insertion into the proximal C-C bond of aminomethylcyclopropanes to generate rhodacyclopentanone intermediates. These are trapped by N-tethered alkenes to provide complex perhydroisoindoles. ...[more]