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Assessing the intracellular fate of rhodium(ii) complexes.

ABSTRACT: Rhodium(ii)-fluorophore conjugates have strong rhodium-based fluorescence quenching that can be harnessed to report on a conjugate's cellular uptake and the intracellular decomposition rate. Information gleened from this study allowed the design of an improved STAT3 metalloinhibitor.

SUBMITTER: Minus MB

PROVIDER: S-EPMC5076564 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature

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Assessing the intracellular fate of rhodium(ii) complexes.

Minus Matthew B MB Kang Marci K MK Knudsen Sarah E SE Liu Wei W Krueger Michael J MJ Smith Morgen L ML Redell Michele S MS Ball Zachary T ZT

Chemical communications (Cambridge, England) 20160901 78

Rhodium(ii)-fluorophore conjugates have strong rhodium-based fluorescence quenching that can be harnessed to report on a conjugate's cellular uptake and the intracellular decomposition rate. Information gleened from this study allowed the design of an improved STAT3 metalloinhibitor. ...[more]

PMID: 27709185

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