Ontology highlight
ABSTRACT:
SUBMITTER: Sommese RF
PROVIDER: S-EPMC5079250 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Sommese R F RF Hariadi R F RF Kim K K Liu M M Tyska M J MJ Sivaramakrishnan S S
Protein science : a publication of the Protein Society 20160831 11
DNA nanostructures have become an important and powerful tool for studying protein function over the last 5 years. One of the challenges, though, has been the development of universal methods for patterning protein complexes on DNA nanostructures. Herein, we present a new approach for labeling DNA nanostructures by functionalizing them with a GFP nanobody. We demonstrate the ability to precisely control protein attachment via our nanobody linker using two enzymatic model systems, namely adenylyl ...[more]