Ontology highlight
ABSTRACT:
SUBMITTER: Sun X
PROVIDER: S-EPMC5082825 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Sun Xiangwei X Hu Yingying Y Zhang Liang L Hu Changyuan C Guo Gangqiang G Mao Chenchen C Xu Jianfeng J Ye Sisi S Huang Guanli G Xue Xiangyang X Guo Aizhen A Shen Xian X
PloS one 20161027 10
<h4>Background</h4>Colorectal cancer (CRC) is one of the deadliest tumours, but its pathogenesis remains unclear. The involvement of differentially expressed long non-coding RNAs (lncRNAs) in CRC tumorigenesis makes them suitable tumour biomarkers.<h4>Methods/findings</h4>Here, we screened 150 cases of CRC and 85 cases of paracancerous tissues in the GEO database for differentially expressed lncRNAs. The levels of lncRNA candidates in 84 CRC and paracancerous tissue samples were validated by qRT ...[more]