Ontology highlight
ABSTRACT:
SUBMITTER: Kiiski JI
PROVIDER: S-EPMC5095781 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Kiiski Johanna I JI Fagerholm Rainer R Tervasmäki Anna A Pelttari Liisa M LM Khan Sofia S Jamshidi Maral M Mantere Tuomo T Pylkäs Katri K Bartek Jiri J Bartkova Jirina J Mannermaa Arto A Tengström Maria M Kosma Veli-Matti VM Winqvist Robert R Kallioniemi Anne A Aittomäki Kristiina K Blomqvist Carl C Nevanlinna Heli H
International journal of cancer 20160919 12
Breast cancer (BC) is a heterogeneous disease, and different tumor characteristics and genetic variation may affect the clinical outcome. The FANCM c.5101C > T nonsense mutation in the Finnish population associates with increased risk of breast cancer, especially for triple-negative breast cancer patients. To investigate the association of the mutation with disease prognosis, we studied tumor phenotype, treatment outcome, and patient survival in 3,933 invasive breast cancer patients, including 1 ...[more]