Ontology highlight
ABSTRACT:
SUBMITTER: Davies MJ
PROVIDER: S-EPMC5096014 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Davies M J MJ Russell-Jones D D Selam J-L JL Bailey T S TS Kerényi Z Z Luo J J Bue-Valleskey J J Iványi T T Hartman M L ML Jacobson J G JG Jacober S J SJ
Diabetes, obesity & metabolism 20160812 11
<h4>Aims</h4>To compare, in a double-blind, randomized, multi-national study, 52- or 78-week treatment with basal insulin peglispro or insulin glargine, added to pre-study oral antihyperglycaemic medications, in insulin-naïve adults with type 2 diabetes.<h4>Material and methods</h4>The primary outcome was non-inferiority of peglispro to glargine with regard to glycated haemoglobin (HbA1c) reduction (margin = 0.4%). Six gated secondary objectives with statistical multiplicity adjustments focused ...[more]