Ontology highlight
ABSTRACT:
SUBMITTER: Trinh HK
PROVIDER: S-EPMC5103193 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Scientific reports 20161110
Sphingolipid (SL) metabolites have been suggested to be important inflammatory mediators in airway inflammation and asthma. However, little is known about SL metabolites in aspirin-exacerbated respiratory disease (AERD). We aimed to explore the potential AERD biomarkers by conducting lipidomics targeting SL metabolites. The levels of SL metabolites in serum and urine samples from 45 AERD patients and 45 aspirin-tolerant asthma (ATA) patients were quantified through mass spectrometry. During the ...[more]