Ontology highlight
ABSTRACT:
SUBMITTER: Holman HA
PROVIDER: S-EPMC5112219 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Holman Holly A HA Tran Vy M VM Kalita Mausam M Nguyen Lynn N LN Arungundram Sailaja S Kuberan Balagurunathan B Rabbitt Richard D RD
Journal of the Association for Research in Otolaryngology : JARO 20160912 6
We report on a new xyloside conjugated to BODIPY, BX and its utility to prime fluorescent glycosaminoglycans (BX-GAGs) within the inner ear in vivo. When BX is administered directly into the endolymphatic space of the oyster toadfish (Opsanus tau) inner ear, fluorescent BX-GAGs are primed and become visible in the sensory epithelia of the semicircular canals, utricle, and saccule. Confocal and 2-photon microscopy of vestibular organs fixed 4 h following BX treatment, reveal BX-GAGs constituting ...[more]