Ontology highlight
ABSTRACT:
SUBMITTER: Dueck HR
PROVIDER: S-EPMC5122016 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Dueck Hannah R HR Ai Rizi R Camarena Adrian A Ding Bo B Dominguez Reymundo R Evgrafov Oleg V OV Fan Jian-Bing JB Fisher Stephen A SA Herstein Jennifer S JS Kim Tae Kyung TK Kim Jae Mun Hugo JM Lin Ming-Yi MY Liu Rui R Mack William J WJ McGroty Sean S Nguyen Joseph D JD Salathia Neeraj N Shallcross Jamie J Souaiaia Tade T Spaethling Jennifer M JM Walker Christopher P CP Wang Jinhui J Wang Kai K Wang Wei W Wildberg Andre A Zheng Lina L Chow Robert H RH Eberwine James J Knowles James A JA Zhang Kun K Kim Junhyong J
BMC genomics 20161124 1
<h4>Background</h4>Recently, measurement of RNA at single cell resolution has yielded surprising insights. Methods for single-cell RNA sequencing (scRNA-seq) have received considerable attention, but the broad reliability of single cell methods and the factors governing their performance are still poorly known.<h4>Results</h4>Here, we conducted a large-scale control experiment to assess the transfer function of three scRNA-seq methods and factors modulating the function. All three methods detect ...[more]