Ontology highlight
ABSTRACT:
SUBMITTER: Yang Y
PROVIDER: S-EPMC5123830 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Yang Yuan Y Song Meifang M Liu Yu Y Liu Hong H Sun Lin L Peng Youming Y Liu Fuyou F Venkatachalam Manjeri A MA Dong Zheng Z
Pharmacology & therapeutics 20160422
Acute kidney injury (AKI) is a major renal disease associated with high mortality rate and increasing prevalence. Decades of research have suggested numerous chemical and biological agents with beneficial effects in AKI. In addition, cell therapy and molecular targeting have been explored for reducing kidney tissue damage and promoting kidney repair or recovery from AKI. Mechanistically, these approaches may mitigate oxidative stress, inflammation, cell death, and mitochondrial and other organel ...[more]