Prostate Cancer Patients-Negative Biopsy Controls Discrimination by Untargeted Metabolomics Analysis of Urine by LC-QTOF: Upstream Information on Other Omics.
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ABSTRACT:
SUBMITTER: Fernandez-Peralbo MA
PROVIDER: S-EPMC5133625 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Publications
Prostate Cancer Patients-Negative Biopsy Controls Discrimination by Untargeted Metabolomics Analysis of Urine by LC-QTOF: Upstream Information on Other Omics.
Fernández-Peralbo M A MA Gómez-Gómez E E Calderón-Santiago M M Carrasco-Valiente J J Ruiz-García J J Requena-Tapia M J MJ Luque de Castro M D MD Priego-Capote F F
Scientific reports 20161202
The existing clinical biomarkers for prostate cancer (PCa) diagnosis are far from ideal (e.g., the prostate specific antigen (PSA) serum level suffers from lack of specificity, providing frequent false positives leading to over-diagnosis). A key step in the search for minimum invasive tests to complement or replace PSA should be supported on the changes experienced by the biochemical pathways in PCa patients as compared to negative biopsy control individuals. In this research a comprehensive glo ...[more]
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