Ontology highlight
ABSTRACT:
SUBMITTER: He Z
PROVIDER: S-EPMC5137159 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
He Zhigang Z Hua Jie J Qian Daohai D Gong Jian J Lin Shengping S Xu Chenglei C Wei Ge G Meng Hongbo H Yang Tingsong T Zhou Bo B Song Zhenshun Z
Scientific reports 20161205
The administration of mesenchymal stem cells/multipotent mesenchymal stromal cells (MSCs) to enhance tissue repair is currently undergoing clinical trials. Some studies, including our previous work, have also revealed the beneficial effect of MSCs in severe acute pancreatitis (SAP); however, their mechanisms or mode of action remain controversial. In this study, we demonstrated that intravenously (i.v.)-administered human MSCs (hMSCs) remarkably promoted recovery from experimental SAP without si ...[more]