Ontology highlight
ABSTRACT:
SUBMITTER: Xu R
PROVIDER: S-EPMC5139906 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Xu Ruoyu R Wang Youfu Y Duan Xiaopin X Lu Kuangda K Micheroni Daniel D Hu Aiguo A Lin Wenbin W
Journal of the American Chemical Society 20160216 7
We report the design of a phosphorescence/fluorescence dual-emissive nanoscale metal-organic framework (NMOF), R-UiO, as an intracellular oxygen (O2) sensor. R-UiO contains a Pt(II)-porphyrin ligand as an O2-sensitive probe and a Rhodamine-B isothiocyanate ligand as an O2-insensitive reference probe. It exhibits good crystallinity, high stability, and excellent ratiometric luminescence response to O2 partial pressure. In vitro experiments confirmed the applicability of R-UiO as an intracellular ...[more]