Ontology highlight
ABSTRACT:
SUBMITTER: Le Gars M
PROVIDER: S-EPMC5144734 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Le Gars Mathieu M Kay Alexander W AW Bayless Nicholas L NL Aziz Natali N Dekker Cornelia L CL Swan Gary E GE Davis Mark M MM Blish Catherine A CA
The Journal of infectious diseases 20160921 11
Pregnancy-induced alterations in immunity may contribute to the increased morbidity associated with influenza A virus infection during pregnancy. We characterized the immune response of monocytes and plasmacytoid dendritic cells (pDCs) to influenza A virus infection in 21 pregnant and 21 nonpregnant women. In pregnant women, monocytes and pDCs exhibit an exaggerated proinflammatory immune response to 2 strains of influenza A virus, compared with nonpregnant women, characterized by increased expr ...[more]