Ontology highlight
ABSTRACT:
SUBMITTER: Patel HH
PROVIDER: S-EPMC5152571 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20161025 43
In this report, we describe the generation of remote allylic quaternary stereocenters β, γ, and δ relative to a carbonyl in high enantioselectivity. We utilize a redox-relay Heck reaction between alkenyl triflates and acyclic trisubstituted alkenols of varying chain-lengths. A wide array of terminal (E)-alkenyl triflates are suitable for this process. The utility of this functionalization is validated further by conversion of the products, via simple organic processes to access remotely function ...[more]