Ontology highlight
ABSTRACT:
SUBMITTER: Verwer EE
PROVIDER: S-EPMC5153396 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Verwer E E EE Zegers C M L CM van Elmpt W W Wierts R R Windhorst A D AD Mottaghy F M FM Lambin P P Boellaard R R
EJNMMI physics 20161212 1
<h4>Background</h4>[<sup>18</sup>F]HX4 is a promising new PET tracer developed to identify hypoxic areas in tumor tissue. This study analyzes [<sup>18</sup>F]HX4 kinetics and assesses the performance of simplified methods for quantification of [<sup>18</sup>F]HX4 uptake. To this end, eight patients with non-small cell lung cancer received dynamic PET scans at three different time points (0, 120, and 240 min) after injection of 426 ± 72 MBq [<sup>18</sup>F]HX4, each lasting 30 min. Several compar ...[more]