Ontology highlight
ABSTRACT:
SUBMITTER: Chiurillo MA
PROVIDER: S-EPMC5177640 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Chiurillo Miguel A MA Moraes Barros Roberto R RR Souza Renata T RT Marini Marjorie M MM Antonio Cristiane R CR Cortez Danielle R DR Curto María Á MÁ Lorenzi Hernán A HA Schijman Alejandro G AG Ramirez José L JL da Silveira José F JF
Frontiers in microbiology 20161222
<i>Trypanosoma cruzi</i> chromosome ends are enriched in surface protein genes and pseudogenes (e.g., trans-sialidases) surrounded by repetitive sequences. It has been proposed that the extensive sequence variability among members of these protein families could play a role in parasite infectivity and evasion of host immune response. In previous reports we showed evidence suggesting that sequences located in these regions are subjected to recombination. To support this hypothesis we introduced a ...[more]