Ontology highlight
ABSTRACT:
SUBMITTER: Babic A
PROVIDER: S-EPMC5181854 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Babic Ana A Bao Ying Y Qian Zhi Rong ZR Yuan Chen C Giovannucci Edward L EL Aschard Hugues H Kraft Peter P Amundadottir Laufey T LT Stolzenberg-Solomon Rachael R Morales-Oyarvide Vicente V Ng Kimmie K Stampfer Meir J MJ Ogino Shuji S Buring Julie E JE Sesso Howard D HD Gaziano John Michael JM Rifai Nader N Pollak Michael N MN Anderson Matthew L ML Cochrane Barbara B BB Luo Juhua J Manson JoAnn E JE Fuchs Charles S CS Wolpin Brian M BM
Cancer research 20161025 24
Leptin is an adipokine involved in regulating energy balance, which has been identified as a potential biologic link in the development of obesity-associated cancers, such as pancreatic cancer. In this prospective, nested case-control study of 470 cases and 1,094 controls from five U.S. cohorts, we used conditional logistic regression to evaluate pancreatic cancer risk by prediagnostic plasma leptin, adjusting for race/ethnicity, diabetes, body mass index, physical activity, plasma C-peptide, ad ...[more]