Ontology highlight
ABSTRACT:
SUBMITTER: Ye Y
PROVIDER: S-EPMC5198716 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20161115 50
A method for the palladium-catalyzed fluorination of cyclic vinyl triflates has been developed. As with several previous palladium-catalyzed fluorination reactions using fluoride salts, controlling the regioselectivity presented a challenge in developing a practical synthetic procedure. The addition of triethyl(trifluoromethyl)silane (TESCF<sub>3</sub> ) was found to effectively address this problem and resulted in drastically improved regioselectivities in this palladium-catalyzed fluorination ...[more]