Ontology highlight
ABSTRACT:
SUBMITTER: DeBord MA
PROVIDER: S-EPMC5204360 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Bioorganic & medicinal chemistry letters 20161124 2
A series of C<sup>2</sup>-alkyl substituted N,N'-bis(arylmethyl)imidazolium salts were synthesized, characterized, and tested for their in vitro anti-cancer activity against multiple non-small cell lung cancer cell lines by our group and the National Cancer Institute's-60 human tumor cell line screen to establish a structure-activity relationship. Compounds are related to previously published N,N'-bis(arylmethyl)imidazolium salts but utilize the historical quinoline motif and anion effects to in ...[more]