Ontology highlight
ABSTRACT:
SUBMITTER: Survery S
PROVIDER: S-EPMC5207195 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Survery Sabeen S Moparthi Lavanya L Kjellbom Per P Högestätt Edward D ED Zygmunt Peter M PM Johanson Urban U
The Journal of biological chemistry 20161114 52
Temperature sensors are crucial for animals to optimize living conditions. The temperature response of the ion channel transient receptor potential A1 (TRPA1) is intriguing; some orthologs have been reported to be activated by cold and others by heat, but the molecular mechanisms responsible for its activation remain elusive. Single-channel electrophysiological recordings of heterologously expressed and purified Anopheles gambiae TRPA1 (AgTRPA1), with and without the N-terminal ankyrin repeat do ...[more]