Ontology highlight
ABSTRACT:
SUBMITTER: Snyder PJ
PROVIDER: S-EPMC5209754 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Snyder Peter J PJ Bhasin Shalender S Cunningham Glenn R GR Matsumoto Alvin M AM Stephens-Shields Alisa J AJ Cauley Jane A JA Gill Thomas M TM Barrett-Connor Elizabeth E Swerdloff Ronald S RS Wang Christina C Ensrud Kristine E KE Lewis Cora E CE Farrar John T JT Cella David D Rosen Raymond C RC Pahor Marco M Crandall Jill P JP Molitch Mark E ME Cifelli Denise D Dougar Darlene D Fluharty Laura L Resnick Susan M SM Storer Thomas W TW Anton Stephen S Basaria Shehzad S Diem Susan J SJ Hou Xiaoling X Mohler Emile R ER Parsons J Kellogg JK Wenger Nanette K NK Zeldow Bret B Landis J Richard JR Ellenberg Susan S SS
The New England journal of medicine 20160201 7
<h4>Background</h4>Serum testosterone concentrations decrease as men age, but benefits of raising testosterone levels in older men have not been established.<h4>Methods</h4>We assigned 790 men 65 years of age or older with a serum testosterone concentration of less than 275 ng per deciliter and symptoms suggesting hypoandrogenism to receive either testosterone gel or placebo gel for 1 year. Each man participated in one or more of three trials--the Sexual Function Trial, the Physical Function Tri ...[more]