Ontology highlight
ABSTRACT:
SUBMITTER: Messaoudene M
PROVIDER: S-EPMC5214533 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Messaoudene Meriem M Fregni Giulia G Enot David D Jacquelot Nicolas N Neves Emmanuelle E Germaud Nathalie N Garchon Henri Jean HJ Boukouaci Wahid W Tamouza Ryad R Chanal Johan J Avril Marie-Françoise MF Toubert Antoine A Zitvogel Laurence L Rusakiewicz Sylvie S Caignard Anne A
Oncoimmunology 20160310 12
Given the NK cell-based immunosurveillance of melanoma, we investigated the prognostic value of NKp46 transcript and NKp30 isoform (NKp30A, NKp30B and NKp30C) profiling in blood of 187 melanoma patients including 13 long survivors (LS), metastatic patients that have controlled the disease. Compared to healthy volunteers (HV), patients had reduced amounts of transcripts of the three NKp30 isoforms (NKp30 A, B and C) but similar ratios between NKp30 isoforms (ΔAB, ΔAC, ΔBC). Stratification of pati ...[more]