Ontology highlight
ABSTRACT:
SUBMITTER: Zhang H
PROVIDER: S-EPMC5221516 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Zhang Huaiying H Elbaum-Garfinkle Shana S Langdon Erin M EM Taylor Nicole N Occhipinti Patricia P Bridges Andrew A AA Brangwynne Clifford P CP Gladfelter Amy S AS
Molecular cell 20151001 2
Compartmentalization in cells is central to the spatial and temporal control of biochemistry. In addition to membrane-bound organelles, membrane-less compartments form partitions in cells. Increasing evidence suggests that these compartments assemble through liquid-liquid phase separation. However, the spatiotemporal control of their assembly, and how they maintain distinct functional and physical identities, is poorly understood. We have previously shown an RNA-binding protein with a polyQ-expa ...[more]