Ontology highlight
ABSTRACT:
SUBMITTER: Freedman JE
PROVIDER: S-EPMC5222717 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Freedman Jane E JE Miano Joseph M JM
Arteriosclerosis, thrombosis, and vascular biology 20161117 1
The new millennium heralds an unanticipated surge of genomic information, most notably an expansive class of long noncoding RNAs (lncRNAs). These transcripts, which now outnumber all protein-coding genes, often exhibit the same characteristics as mRNAs (RNA polymerase II-dependent, 5' methyl-capped, multiexonic, polyadenylated); yet, they do not encode for stable, well-conserved proteins. Elucidating the function of all relevant lncRNAs in heart, vasculature, lung, and blood is essential for gen ...[more]