Ontology highlight
ABSTRACT:
SUBMITTER: Pei J
PROVIDER: S-EPMC5227713 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Pei Junrui J Li Bingyun B Liu Yang Y Liu Xiaona X Li Mang M Chu Yanru Y Yang Qing Q Jiang Wei W Chen Fuxun F Darko Gottfried M GM Yang Yanmei Y Gao Yanhui Y
Scientific reports 20170112
Brick tea skeletal fluorosis is still a public health issue in the north-western area of China. However its pathogenesis remains unknown. Our previous study reveals that the severity of skeletal fluorosis in Tibetans is more serious than that in Kazaks, although they have similar fluoride exposure, suggesting the onset of brick tea type skeletal fluorosis might be genetically influenced. Here we show that MMP-2 rs2287074 SNP (G/A), but not rs243865, was associated with Brick tea type fluorosis i ...[more]