Free breathing three-dimensional late gadolinium enhancement cardiovascular magnetic resonance using outer volume suppressed projection navigators.

ABSTRACT: To develop a three-dimensional, free-breathing, late gadolinium enhancement (3D FB-LGE) cardiovascular magnetic resonance (CMR) technique, and to compare it with clinically used two-dimensional breath-hold LGE (2D BH-LGE).The proposed 3D FB-LGE method consisted of inversion preparation, inversion delay, fat saturation, outer volume suppression, one-dimensional projection navigators, and a segmented stack of spirals acquisition. The 3D FB-LGE and 2D BH-LGE scans were performed on 29 cardiac patients. Qualitative analysis and quantitative analysis (in patients with scar) were performed.No significant differences were noted between the 3D FB-LGE and 2D BH-LGE data sets in terms of overall image quality score (2D: 4.69?±?0.60 versus 3D: 4.55?±?0.51, P?=?0.46) and image artifact score (2D: 1.10?±?0.31 versus 3D: 1.17?±?0.38; P?=?0.63). The average difference in fractional scar volume between the 3D and 2D methods was 1.9% (n?=?5). Acquisition time was significantly shorter for the 3D FB-LGE over 2D BH-LGE by a factor of 2.83?±?0.77 (P?

SUBMITTER: Menon RG 

PROVIDER: S-EPMC5247353 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature