Ontology highlight
ABSTRACT:
SUBMITTER: Pan J
PROVIDER: S-EPMC5249260 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Science advances 20170120 1
DNA walkers are designed with the structural specificity and functional diversity of oligonucleotides to actively convert chemical energy into mechanical translocation. Compared to natural protein motors, DNA walkers' small translocation distance (mostly <100 nm) and slow reaction rate (<0.1 nm s<sup>-1</sup>) make single-molecule characterization of their kinetics elusive. An important indication of single-walker kinetics is the rate-limiting reactions that a particular walker design bears. We ...[more]