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Fibronectin-binding protein gene recombination and horizontal transfer between group A and G streptococci.


ABSTRACT: We report evidence of interspecies gene transfer between the important virulence factor genes sfbI and gfbA. Because the identified group G streptococcus gfbA types possess DNA cassettes that can be identified in a number of group A streptococcus strains, it appears that homologous recombination is occurring between these species.

SUBMITTER: Towers RJ 

PROVIDER: S-EPMC525228 | biostudies-literature | 2004 Nov

REPOSITORIES: biostudies-literature

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Fibronectin-binding protein gene recombination and horizontal transfer between group A and G streptococci.

Towers Rebecca J RJ   Gal Daniel D   McMillan David D   Sriprakash Kadaba S KS   Currie Bart J BJ   Walker Mark J MJ   Chhatwal Gursharan S GS   Fagan Peter K PK  

Journal of clinical microbiology 20041101 11


We report evidence of interspecies gene transfer between the important virulence factor genes sfbI and gfbA. Because the identified group G streptococcus gfbA types possess DNA cassettes that can be identified in a number of group A streptococcus strains, it appears that homologous recombination is occurring between these species. ...[more]

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