Ontology highlight
ABSTRACT:
SUBMITTER: Coretti L
PROVIDER: S-EPMC5299173 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Coretti Lorena L Natale Alessandro A Cuomo Mariella M Florio Ermanno E Keller Simona S Lembo Francesca F Chiariotti Lorenzo L Pero Raffaela R
Mediators of inflammation 20170126
Crohn's disease (CD) is a chronic inflammation of the intestinal mucosa, characterized by periods of acute recurrence and remission. Depending on the specific region affected, CD is classified as ileal CD or colonic CD. It is largely accepted that the intestinal microbiota is involved in the onset of the pathology. Indeed, a reduced immune tolerance to components of the intestinal commensal microbiota and inflammation of the intestinal barrier typifies patients with CD. Several studies have show ...[more]