Ontology highlight
ABSTRACT:
SUBMITTER: Sechi S
PROVIDER: S-EPMC5303273 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Sechi Stefano S Frappaolo Anna A Fraschini Roberta R Capalbo Luisa L Gottardo Marco M Belloni Giorgio G Glover David M DM Wainman Alan A Giansanti Maria Grazia MG
Open biology 20170101 1
Cytokinesis requires a tight coordination between actomyosin ring constriction and new membrane addition along the ingressing cleavage furrow. However, the molecular mechanisms underlying vesicle trafficking to the equatorial site and how this process is coupled with the dynamics of the contractile apparatus are poorly defined. Here we provide evidence for the requirement of Rab1 during cleavage furrow ingression in cytokinesis. We demonstrate that the gene omelette (omt) encodes the Drosophila ...[more]