Ontology highlight
ABSTRACT:
SUBMITTER: Hee JS
PROVIDER: S-EPMC5313200 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Hee Jia Shee JS Cresswell Peter P
PloS one 20170216 2
Viperin is an antiviral protein that is upregulated by interferons and by ligands for a variety of innate immune receptors. It possesses diverse capabilities and functions in an array of viral infections. Studies have shown that it appears to be particularly important in defence against RNA viruses, such as West Nile, Dengue, and Chikungunya viruses, although the specific mechanisms involved are not well understood at the molecular level. Here we identify the mitochondrial antiviral signalling p ...[more]