Ontology highlight
ABSTRACT:
SUBMITTER: Carpenter D
PROVIDER: S-EPMC5319014 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Carpenter Danielle D Mitchell Laura M LM Armour John A L JA
Human genomics 20170220 1
<h4>Background</h4>Salivary amylase in humans is encoded by the copy variable gene AMY1 in the amylase gene cluster on chromosome 1. Although the role of salivary amylase is well established, the consequences of the copy number variation (CNV) at AMY1 on salivary amylase protein production are less well understood. The amylase gene cluster is highly structured with a fundamental difference between odd and even AMY1 copy number haplotypes. In this study, we aimed to explore, in samples from 119 u ...[more]