Ontology highlight
ABSTRACT:
SUBMITTER: Hendrickson TW
PROVIDER: S-EPMC532023 | biostudies-literature | 2004 Dec
REPOSITORIES: biostudies-literature
Hendrickson Triscia W TW Perrone Catherine A CA Griffin Paul P Wuichet Kristin K Mueller Joshua J Yang Pinfen P Porter Mary E ME Sale Winfield S WS
Molecular biology of the cell 20041006 12
Increased phosphorylation of dynein IC IC138 correlates with decreases in flagellar microtubule sliding and phototaxis defects. To test the hypothesis that regulation of IC138 phosphorylation controls flagellar bending, we cloned the IC138 gene. IC138 encodes a novel protein with a calculated mass of 111 kDa and is predicted to form seven WD-repeats at the C terminus. IC138 maps near the BOP5 locus, and bop5-1 contains a point mutation resulting in a truncated IC138 lacking the C terminus, inclu ...[more]