Ontology highlight
ABSTRACT:
SUBMITTER: Porter ME
PROVIDER: S-EPMC25196 | biostudies-literature | 1999 Mar
REPOSITORIES: biostudies-literature
Porter M E ME Bower R R Knott J A JA Byrd P P Dentler W W
Molecular biology of the cell 19990301 3
A second cytoplasmic dynein heavy chain (cDhc) has recently been identified in several organisms, and its expression pattern is consistent with a possible role in axoneme assembly. We have used a genetic approach to ask whether cDhc1b is involved in flagellar assembly in Chlamydomonas. Using a modified PCR protocol, we recovered two cDhc sequences distinct from the axonemal Dhc sequences identified previously. cDhc1a is closely related to the major cytoplasmic Dhc, whereas cDhc1b is closely rela ...[more]