Ontology highlight
ABSTRACT:
SUBMITTER: Thind K
PROVIDER: S-EPMC5330603 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Thind Komal K Padrnos Leslie J LJ Ramanathan Ramesh K RK Borad Mitesh J MJ
Therapeutic advances in gastroenterology 20161017 1
Pancreatic cancer is a highly aggressive and lethal cancer characterized by high invasiveness, local and extensive dissemination at time of diagnosis and resistance to treatment. Few therapies have shown efficacy in the past and even standard of care therapies yield only modest improvements in the mortality of patients with advanced or metastatic disease. Efforts have been undertaken to study the pancreatic tumor microenvironment and have established its complex and immunosuppressive nature whic ...[more]