Computational modeling of the cell-autonomous mammalian circadian oscillator.
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ABSTRACT:
SUBMITTER: Podkolodnaya OA
PROVIDER: S-EPMC5333193 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Publications
Computational modeling of the cell-autonomous mammalian circadian oscillator.
Podkolodnaya Olga A OA Tverdokhleb Natalya N NN Podkolodnyy Nikolay L NL
BMC systems biology 20170224 Suppl 1
This review summarizes various mathematical models of cell-autonomous mammalian circadian clock. We present the basics necessary for understanding of the cell-autonomous mammalian circadian oscillator, modern experimental data essential for its reconstruction and some special problems related to the validation of mathematical circadian oscillator models. This work compares existing mathematical models of circadian oscillator and the results of the computational studies of the oscillating systems ...[more]
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