Ontology highlight
ABSTRACT:
SUBMITTER: Khan SA
PROVIDER: S-EPMC5333839 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Khan Sajjad Ahmad SA Manzoor Sadaf S Alamgir Ali Amjad A Khan Dost Muhammad DM Khalil Umair U
PloS one 20170302 3
Gene-mapping studies, regularly, rely on examination for Mendelian transmission of marker alleles in a pedigree as a way of screening for genotyping errors and mutations. For analysis of family data sets, it is, usually, necessary to resolve or remove the genotyping errors prior to consideration. At the Center of Inherited Disease Research (CIDR), to deal with their large-scale data flow, they formalized their data cleaning approach in a set of rules based on PedCheck output. We scrutinize via c ...[more]