Ontology highlight
ABSTRACT:
SUBMITTER: Tanner R
PROVIDER: S-EPMC5335253 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Tanner Rachel R O'Shea Matthew K MK White Andrew D AD Müller Julius J Harrington-Kandt Rachel R Matsumiya Magali M Dennis Mike J MJ Parizotto Eneida A EA Harris Stephanie S Stylianou Elena E Naranbhai Vivek V Bettencourt Paulo P Drakesmith Hal H Sharpe Sally S Fletcher Helen A HA McShane Helen H
Scientific reports 20170303
The current vaccine against tuberculosis, live attenuated Mycobacterium bovis BCG, has variable efficacy, but development of an effective alternative is severely hampered by the lack of an immune correlate of protection. There has been a recent resurgence of interest in functional in vitro mycobacterial growth inhibition assays (MGIAs), which provide a measure of a range of different immune mechanisms and their interactions. We identified a positive correlation between mean corpuscular haemoglob ...[more]