Ontology highlight
ABSTRACT:
SUBMITTER: Kong HK
PROVIDER: S-EPMC5342445 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Kong Hyun Kyung HK Park Sae Jeong SJ Kim Ye Sol YS Kim Kyoung Min KM Lee Hyun-Woo HW Kang Hyeok-Gu HG Woo Yu Mi YM Park Eun Young EY Ko Je Yeong JY Suzuki Hiromu H Chun Kyung-Hee KH Song Erwei E Jang Kyu Yun KY Park Jong Hoon JH
Oncotarget 20160801 34
The role of lymphocyte antigen 6 complex, locus K (LY6K) in breast cancer has been studied, whereas the epigenetic control of LY6K transcription is not fully understood. Here, we report that breast cancer patients with increased LY6K expression had shorter disease-free and overall survival than the patients with low levels of LY6K by multivariate analysis. LY6K also was upregulated in breast cancer patients with distant metastases than those without distant metastases, downregulating E-cadherin ...[more]