Ontology highlight
ABSTRACT:
SUBMITTER: Cheng HL
PROVIDER: S-EPMC5342485 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Cheng Hsin-Lin HL Liu Yu-Fan YF Su Chun-Wen CW Su Shih-Chi SC Chen Mu-Kuan MK Yang Shun-Fa SF Lin Chiao-Wen CW
Oncotarget 20161001 43
In Taiwan, oral cancer is the fourth leading cancer in males and is associated with exposure to environmental carcinogens. WW domain-containing oxidoreductase (WWOX), a tumor suppressor gene, is associated with the development of various cancers. We hypothesized that genetic variants of WWOX influence the susceptibility to oral cancer. Five polymorphisms of WWOX gene from 761 male patients with oral cancer and 1199 male cancer-free individuals were genotyped. We observed that individuals carryin ...[more]