Ontology highlight
ABSTRACT:
SUBMITTER: Dai X
PROVIDER: S-EPMC5346290 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Dai Xiongfeng X Zhu Manlu M Warren Mya M Balakrishnan Rohan R Patsalo Vadim V Okano Hiroyuki H Williamson James R JR Fredrick Kurt K Wang Yi-Ping YP Hwa Terence T
Nature microbiology 20161212
Bacteria growing under different conditions experience a broad range of demand on the rate of protein synthesis, which profoundly affects cellular resource allocation. During fast growth, protein synthesis has long been known to be modulated by adjusting the ribosome content, with the vast majority of ribosomes engaged at a near-maximal rate of elongation. Here, we systematically characterize protein synthesis by Escherichia coli, focusing on slow-growth conditions. We establish that the transla ...[more]