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Penicillin-Susceptible, Oxidase-Negative, Nonhemolytic, Nonmotile Bacillus megaterium in Disguise of Bacillus anthracis.


ABSTRACT: Bacillus anthracis is a bacterial pathogen of major concern. The spores of this bacteria can survive harsh environmental conditions for extended periods and are well recognized as a potential bioterror weapon with significant implications. Accurate and timely identification of this Bacillus species in the diagnostic laboratory is essential for disease and public health management. Biosafety Level 3 measures and ciprofloxacin treatment were instituted when B. anthracis was suspected from a patient with gangrenous foot. 16S rDNA sequencing was performed to accurately identify the suspected bacterium, due to the superiority of this method to accurately identify clinically isolated bacteria. B. megaterium was identified as the causative agent and the organism was subsequently treated as a Biosafety Level 2 pathogen.

SUBMITTER: Loong SK 

PROVIDER: S-EPMC5346375 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature

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Penicillin-Susceptible, Oxidase-Negative, Nonhemolytic, Nonmotile <i>Bacillus megaterium</i> in Disguise of <i>Bacillus anthracis</i>.

Loong Shih Keng SK   Teoh Boon Teong BT   Johari Jefree J   Khor Chee Sieng CS   Abd-Jamil Juraina J   Nor'e Siti Sarah SS   Samsudin Nur Izyan NI   Azizan Noor Syahida NS   Yaacob Che Norainon CN   CheMatSeri Asma Anati AA   Mahfodz Nur Hidayana NH   AbuBakar Sazaly S  

Case reports in infectious diseases 20170226


<i>Bacillus anthracis</i> is a bacterial pathogen of major concern. The spores of this bacteria can survive harsh environmental conditions for extended periods and are well recognized as a potential bioterror weapon with significant implications. Accurate and timely identification of this <i>Bacillus</i> species in the diagnostic laboratory is essential for disease and public health management. Biosafety Level 3 measures and ciprofloxacin treatment were instituted when <i>B. anthracis</i> was su  ...[more]

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