Ontology highlight
ABSTRACT:
SUBMITTER: Varda-Bloom N
PROVIDER: S-EPMC5352130 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Oncotarget 20170101 1
Allogeneic stem cell transplantation remains the standard treatment for resistant advanced chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia. Relapse is the major cause of treatment failure in both diseases. Post-allo-SCT administration of TKIs could potentially reduce relapse rates, but concerns regarding their effect on immune reconstitution have been raised. We aimed to assess immune functions of 12 advanced CML and Ph+ ALL patients who received post-a ...[more]