Ontology highlight
ABSTRACT:
SUBMITTER: Gao B
PROVIDER: S-EPMC5355251 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Gao Boning B Huang Chunxian C Kernstine Kemp K Pelekanou Vasiliki V Kluger Yuval Y Jiang Tingting T Peters-Hall Jennifer R JR Coquelin Melissa M Girard Luc L Zhang Wei W Huffman Kenneth K Oliver Dwight D Kinose Fumi F Haura Eric E Teer Jamie K JK Rix Uwe U Le Anh T AT Aisner Dara L DL Varella-Garcia Marileila M Doebele Robert C RC Covington Kyle R KR Hampton Oliver A OA Doddapaneni Harsha V HV Jayaseelan Joy C JC Hu Jianhong J Wheeler David A DA Shay Jerry W JW Rimm David L DL Gazdar Adi A Minna John D JD
Oncotarget 20170201 7
The "conditionally reprogrammed cells" (CRC) method, using a Rho kinase inhibitor and irradiated mouse fibroblast cells has been described for the efficient growth of cells from malignant and non-malignant samples from primary tumor and non-malignant sites. Using the CRC method, four institutions independently cultured tumor tissues from 48 non-small cell lung cancers (NSCLC, mostly from primary resected tumors) and 22 non-malignant lungs. We found that epithelial cells could be cultured from tu ...[more]