Ontology highlight
ABSTRACT:
SUBMITTER: Shah R
PROVIDER: S-EPMC5360281 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Shah Ravi R Murthy Venkatesh V Pacold Michael M Danielson Kirsty K Tanriverdi Kahraman K Larson Martin G MG Hanspers Kristina K Pico Alexander A Mick Eric E Reis Jared J de Ferranti Sarah S Freinkman Elizaveta E Levy Daniel D Hoffmann Udo U Osganian Stavroula S Das Saumya S Freedman Jane E JE
Diabetes care 20170209 4
<h4>Objective</h4>Insulin resistance (IR) is a hallmark of obesity and metabolic disease. Circulating extracellular RNAs (ex-RNAs), stable RNA molecules in plasma, may play a role in IR, though most studies on ex-RNAs in IR are small. We sought to characterize the relationship between ex-RNAs and metabolic phenotypes in a large community-based human cohort.<h4>Research design and methods</h4>We measured circulating plasma ex-RNAs in 2,317 participants without diabetes in the Framingham Heart Stu ...[more]