Ontology highlight
ABSTRACT:
SUBMITTER: Dong Q
PROVIDER: S-EPMC5362516 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Dong Qianze Q Fu Lin L Zhao Yue Y Xie Chengyao C Li Qingchang Q Wang Enhua E
Oncotarget 20170201 9
Although TNFAIP8 overexpression has been implicated in several human cancers, its clinical significance and biological function in hepatocellular carcinoma (HCC) remains unknown. Our study demonstrated that TNFAIP8 overexpression in primary HCC samples correlated with TNM stage, recurrence, poor prognosis and served as an independent favorable prognostic factor. We further showed that TNFAIP8 upregulated cell proliferation, migration, invasion and xenograft tumor growth of HCC cells. In addition ...[more]