Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals.
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ABSTRACT:
SUBMITTER: Ighodaro ET
PROVIDER: S-EPMC5363738 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Publications
Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals.
Ighodaro Eseosa T ET Abner Erin L EL Fardo David W DW Lin Ai-Ling AL Katsumata Yuriko Y Schmitt Frederick A FA Kryscio Richard J RJ Jicha Gregory A GA Neltner Janna H JH Monsell Sarah E SE Kukull Walter A WA Moser Debra K DK Appiah Frank F Bachstetter Adam D AD Van Eldik Linda J LJ Nelson Peter T PT
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20160106 1
Risk factors and cognitive sequelae of brain arteriolosclerosis pathology are not fully understood. To address this, we used multimodal data from the National Alzheimer's Coordinating Center and Alzheimer's Disease Neuroimaging Initiative data sets. Previous studies showed evidence of distinct neurodegenerative disease outcomes and clinical-pathological correlations in the "oldest-old" compared to younger cohorts. Therefore, using the National Alzheimer's Coordinating Center data set, we analyze ...[more]
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