Unknown

Dataset Information

0

Neurologic Deficits Have a Negative Impact on Patient-Related Outcomes in Primary Presentation Adult Symptomatic Lumbar Scoliosis Surgical Treatment at One-Year Follow-up.


ABSTRACT: A retrospective analysis of prospective, multicenter National Institute of Health clinical trial.The aim of this study was to assess the rate of neurologic complications and impact of new neurologic deficits on 1-year postoperative patient-reported outcomes (PROs).There are limited studies evaluating the impact of new neurologic deficits on PROs following surgery for primary presentation adult lumbar scoliosis.Patients were divided into two groups: new postoperative neurological deficit (Def) or no deficit (NoDef). Preoperative and 1-year follow-up PROs were analyzed [Scoliosis Research Society (SRS) Questionnaire, Oswestry Disability Index (ODI), Short Form-12 Physical/Mental Health Composite Scores (PCS/MCS), and back/leg pain Numerical Rating Scale (NRS)].One hundred forty-one patients: 14 Def (9.9%), 127 NoDef (90.1%). No differences were observed in demographic, radiographic, or PRO data between groups preoperatively. Def group had longer surgical procedures (8.3 vs. 6.9?hours, P?=?0.030), greater blood loss (2832 vs. 2606?mL, P?=?0.022), and longer hospitalizations (10.6 vs. 7.8 days, P?=?0.004). NoDef group reported significant improvement in all PROs from preop to 1-year postoperative. Def group only had improvement in SRS Pain (2.7 preop to 3.4 postop, P?=?0.037) and self-image domains (2.7 to 3.6, p?=?0.004), and NRS back pain (6.6 to 3.2, P?=?0.004) scores with significant worsening of NRS leg pain (4.1 to 6.1, P?=?0.045). Group comparisons of 1-year postop PROs found that Def group reported more NRS leg pain (6.1 vs. 1.7, P?

SUBMITTER: Kang DG 

PROVIDER: S-EPMC5373095 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature

altmetric image

Publications

Neurologic Deficits Have a Negative Impact on Patient-Related Outcomes in Primary Presentation Adult Symptomatic Lumbar Scoliosis Surgical Treatment at One-Year Follow-up.

Kang Daniel G DG   Baldus Christine C   Glassman Steven D SD   Shaffrey Christopher I CI   Lurie Jon D JD   Bridwell Keith H KH  

Spine 20170401 7


<h4>Study design</h4>A retrospective analysis of prospective, multicenter National Institute of Health clinical trial.<h4>Objective</h4>The aim of this study was to assess the rate of neurologic complications and impact of new neurologic deficits on 1-year postoperative patient-reported outcomes (PROs).<h4>Summary of background data</h4>There are limited studies evaluating the impact of new neurologic deficits on PROs following surgery for primary presentation adult lumbar scoliosis.<h4>Methods<  ...[more]

Similar Datasets

| S-EPMC3111518 | biostudies-literature
| S-EPMC6738555 | biostudies-literature
| S-EPMC5841946 | biostudies-literature
2005-01-18 | GSE1907 | GEO
| PRJEB3227 | ENA
| S-EPMC7764638 | biostudies-literature
| S-EPMC4792651 | biostudies-literature
| S-EPMC8424260 | biostudies-literature
| S-EPMC5901523 | biostudies-literature
| S-EPMC5454130 | biostudies-literature