Ontology highlight
ABSTRACT:
SUBMITTER: Chu H
PROVIDER: S-EPMC5384674 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Chu Hongwei H Sun Pin P Yin Jiahui J Liu Guangming G Wang Yiwei Y Zhao Pengyao P Zhu Yizhun Y Yang Xiaohan X Zheng Tiezheng T Zhou Xuezhong X Jin Weilin W Sun Changkai C
PloS one 20170407 4
Epilepsy is a complex neurological disorder and a significant health problem. The pathogenesis of epilepsy remains obscure in a significant number of patients and the current treatment options are not adequate in about a third of individuals which were known as refractory epilepsies (RE). Network medicine provides an effective approach for studying the molecular mechanisms underlying complex diseases. Here we integrated 1876 disease-gene associations of RE and located those genes to human protei ...[more]